Drugs can be administered to a patient in various forms. They are available in solid, semisolid and liquid dosage forms.
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Drug distribution
Distribution is defined as the reversible transfer of drugs between body fluid compartments. After absorption, a drug enters the systemic circulation and is distributed in the body fluids.
Staining Techniques Used in Microbiology
Staining is necessary to produce color contrast and thereby increase the visibility of the object. Before staining, the fixation of the smear to the slide is done:
Botulism (Etiology, Pathogenesis, Clinical Signs, Diagnosis, Treatment, And Control)
Clostridium botulinum produces potent neurotoxins during their vegetative transformation.
Milk Fever (Etiology, pathogenesis, clinical signs, diagnosis, treatment, and control)
• A disease of adult female bovine occurring around the parturition and caused by hypocalcemia, characterized by weakness, recumbency, paresis, shock, and death.
Gram staining of bacteria (Principle of Gram staining and steps in Grams’ staining procedure)
The structure of the organism’s cell wall determines whether the organism is gram-positive or negative. When stained with a primary stain and fixed by a mordant, some bacteria can retain the primary stain by resisting decolorization while others get decolorized by a decolorizer.
Drug Absorption & Factors Influencing Drug Absorption
The movement of a drug from the site of administration into the bloodstream is known as absorption.
Difference between bacterial endotoxin and exotoxin
Difference between bacterial endotoxin and exotoxin
Chloramphenicol (Pharmacokinetics, pharmacodynamics)
Chloramphenicol is a bacteriostatic broad-spectrum antibiotic, active against both aerobic and anaerobic gram +ve & gram –ve organisms.
Bioavailability of drugs (Distribution)
It is the fraction of a drug that reaches the systemic circulation from a given dose. The intravenous route of drug administration gives 100% bioavailability, as it directly enters the circulation.