Category: Pharmacology

World Health Organisation (WHO) defines drug as ‘any substance or product that is used or intended to be used to modify or explore physiological systems or pathological states for the benefit of the recipient’.

Tuberculosis (TB) is a chronic infectious disease caused by M. tuberculosis, an acid-fast bacillus (AFB).
Mycobacterial infections require prolonged treatment. Since TB is a chronic infection, it consists of excessive fibrous tissue with central necrosis. So vascularity of the lesion is poor; hence, the penetration of the drug into the lesion is decreased.

Antiseptic: It is an agent used to eliminate microorganisms on living tissues.
Disinfectant: It is an agent used to eliminate microorganisms on inanimate objects.

The use of antifungal drugs in human and veterinary medicine has increased in recent years.

with virus-specific events in replication, including viral attachment, uncoating, assembly, and virus-directed macromolecular synthesis. As a result, antiviral agents typically have a restricted spectrum of activity.

Benzimidazoles bind to β-tubulin within a variety of helminths and protozoa. This leads to inhibition of tubulin polymerization and the formation of microtubules, with impaired cell division.